Panic in the Streets (1950) semidocumentary film noir directed by Elia Kazan shot exclusively on location in New Orleans, Louisiana and featuring numerous New Orleans citizens in speaking and non-speaking roles.
The film tells the story of Clinton Reed, an officer of the U.S. Public Health Service (played by Richard Widmark) and a police captain (Paul Douglas) who have only a day or two in which to prevent an epidemic of pneumonic plague after Reed determines a waterfront homicide victim is an index case. Co-stars include Barbara Bel Geddes (as Reed’s wife Nancy), Walter Jack Palance (in his film debut) and Zero Mostel ” the latter two play associates of the victim who had prompted the investigation. The film was also the debut of Tommy Rettig, who played the Reeds’ son. wiki



